What’s Osteoporosis and What Causes It?
Osteoporosis is just a bone diseases occurring when the body loses too much bone, makes inadequate bone, or both. Consequently, bones become weak and may break from a drop or, in serious cases, from sneezing or minor bumps.
Osteoporosis means “porous bone.” Viewed under a microscope, healthy bone appears like a honeycomb. When osteoporosis occurs, the holes and spaces in the honeycomb are much larger than in healthy bone. Osteoporotic bones have lost density or mass and contain abnormal tissue structure. As bones become less dense, they weaken and are prone to break. If you’re 50 or older and have broken a bone, ask your doctor or healthcare provider of a bone density test.
Osteoporosis is Common
About 54 million Americans have osteoporosis and low bone mass, placing them at increased risk for osteoporosis. Studies claim that approximately one in two women and up to at least one in four men age 50 and older will break a bone due to osteoporosis.
Osteoporosis is Serious
Breaking a bone is just a serious complication of osteoporosis, especially with older patients. Osteoporotic bone breaks are most likely to happen in the hip, spine or wrist, but other bones can break too. Along with causing permanent pain, osteoporosis causes some patients to get rid of height. When osteoporosis affects vertebrae, or the bones of the spine, it often contributes to a stooped or hunched posture.
Osteoporosis may limit mobility, which frequently contributes to feelings of isolation or depression. Additionally, twenty percent of seniors who break a hip die within 12 months from either complications linked to the broken bone itself or the surgery to correct it. Many patients require long-term nursing home care.
Osteoporosis is Costly
Osteoporosis is responsible for two million broken bones and $19 billion in related costs every year. By 2025, experts predict that osteoporosis will be responsible for approximately three million fractures and $25.3 billion in costs annually.
Osteoporosis Can Sneak up on You
Osteoporosis is often called a silent disease because one can’t feel bones weakening. Breaking a bone is the first sign of osteoporosis or a patient may notice he said or she gets shorter or their upper back is curving forward. If you’re experiencing height loss or your spine is curving, be sure to consult your doctor or healthcare professional immediately.
Diseases, Conditions and Medical Procedures That May Cause Bone Loss
There are lots of health problems and a few medical procedures that raise the likelihood of osteoporosis. When you yourself have some of the following diseases or conditions, talk to your doctor or healthcare provider about what you can do to help keep your bones healthy.
Medicines that May Cause Bone Loss
Some medicines may be harmful to your bones, even although you need to take them for another condition. Bone diseases is generally greater for the medication in high doses and for an extended time.
It’s crucial that you talk to your healthcare provider in regards to the risks and advantages of any medicines you take and about how exactly they could affect your bones, but don’t stop any treatment or change the dose of your medicines unless your healthcare provider says it’s safe to accomplish so. If you want to have a medicine that produces bone loss, work with your healthcare provider to find out the best possible dose you can try control your symptoms.
The next medicines could cause bone loss:
Antiseizure medicines (only some) such as for example Dilantin® or Phenobarbital
Aromatase inhibitors such as Arimidex®, Aromasin® and Femara®
Cancer chemotherapeutic drugs
Cyclosporine A and FK506 (Tacrolimus)
Gonadotropin releasing hormone (GnRH) such as for example Lupron® and Zoladex®
Medroxyprogesterone acetate for contraception (Depo-Provera®)
Proton pump inhibitors (PPIs) such as for example Nexium®, Prevacid® and Prilosec®
Selective serotonin reuptake inhibitors (SSRIs) such as for example Lexapro®, Prozac® and Zoloft®
Steroids (glucocorticoids) such as cortisone and prednisone
Tamoxifen® (premenopausal use)
Thiazolidinediones such as Actos® and Avandia®
Thyroid hormones in excess
Osteoporosis and Steroid Medicines
While steroid medicines can be lifesaving treatments for some conditions, they can also cause bone diseases and osteoporosis. These medicines in many cases are referred to as steroids, glucocorticoids or corticosteroids. They should not be confused with anabolic steroids, which are male hormones that some athletes use to build muscle.
Steroids are much like certain hormones created by your own body. Healthcare providers prescribe them for several conditions, including rheumatoid arthritis (but not osteoarthritis), asthma, Crohn’s disease, lupus and allergies. They’re often prescribed to relieve inflammation. They are also used as well as other medicines to take care of cancer and autoimmune conditions and to guide organ transplants. Common steroid medicines are cortisone, dexamethasone (Decadron®), methylprednisolone (Medrol®) and prednisone. Intravenous forms include methylprednisolone sodium succinate (Solu-Medrol®).
Taking steroid medicines as pills in an amount of 5 mg or more for three or even more months can increase the chance of bone loss and developing osteoporosis. Talk with your healthcare provider about taking the cheapest dose for the shortest time period for your condition. If you want to take steroid medicines for more than this, you need to take steps to bone disease prevention. While taking steroids, it is especially important to obtain enough calcium and vitamin D. Additionally it is very important to exercise and not smoke. It’s also possible to desire to ask your healthcare provider if you will need a bone density test.